Acne and hirsutism are associated with increased androgen levels. In an Italian study 50 women diagnosed with PCOS used the combination of Myo - Inositol and Folic Acid (product called INOFOLIC®) for three months, it was demonstrated that plasma LH, testosterone, free testosterone and insulin were significantly reduced. In 6 months of taking the product, both hirsutism and acne decreased. The researchers concluded: “MYO [inositol] administration is a simple and safe treatment that ameliorates the metabolic profile of patients with PCOS, reducing hirsutism and acne.” (source:http://www.ncbi.nlm.nih.gov/pubmed/19551544).
Myo – Inositol has demonstrated in combination with Folic Acid (Vitamin B6) in clinical studies a significant improvement in testosterone, triglyceride and insulin levels. The product called INOFOLIC® was used twice daily.
(source: Gerli S, Mignosa M, Di Renzo GC. Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci. 2003;7(6):151–159.)